Diagnostic value of whole -body diffusion weighted imaging added to bone scan in early diagnosis of bone metastases in breast cancer patients

Abstract Background Metastases to the bones are a frequent location of metastasis in advanced breast cancer and responsible for substantial morbidity healthcare expenses. Imaging has been crucial directing patient therapy decades, contributing staging response evaluation skeleton. This research aimed assess diagnostic value whole-body magnetic resonance imaging with diffusion-weighted added radionuclide bone scans early diagnosis metastases patients. Results The study was prospective observational cohort performed on 20 patients suspected metastases. were evaluated first by obtaining detailed personal history. Laboratory tests, including CBC, liver, kidney function tests assessed. All examined MRI (DWIBS; background body signal suppression) images scintigraphy after intravenous injection mci technetium-99m ( 99m Tc) methylene diphosphonate using dual head gamma camera. total number lesions detected scan 74, 75 seen DWIBS. Twenty-four missed Fourteen found free DWIBS examination spine pelvic bones. Conclusions Whole seems be promising method detecting from that could used complementary traditional more accurate tumor, helping determine most appropriate protocol management.